Retina
experience
redefined

RETINA EXPERIENCE

Our retina experience will redefine your retina experience

Our team has unmatched expertise and an impressive track record of innovation in retinal disease

> 0

clinical trials designed or led by our team 

> 0

combined years of treating patients with retinal disease

> 0

treatment launches
across retinal disease  

DISEASE BURDEN

Retinal disease is one of the leading causes of blindness1,2

1.8M

Americans3

Wet Age-Related Macular Degeneration (AMD)

6.4M

Americans3

Non-Proliferative Diabetic Retinopathy (NPDR) 

1.7M

Americans3

Diabetic Macular
Edema (DME) 

TREATMENT BURDEN

Treatments for retinal disease create significant burden on patients and care partners4

Wet AMD treatment creates significant burden on patients and care partners4

Patient Burden

90% of patients currently require injections every 1-3 months, impacting and disrupting lives4,5

Care Partner Burden 

Up to 12 days off from work per year may be needed from care partners for injection or treatment visits5

Poor Long-Term Outcomes 

Frequent injections may result in retinal fluid fluctuations and decreased adherence, which are associated with poor long-term outcomes6

REDEFINING TREATMENT

Ocular aims to transform the
treatment of retinal disease

We aim to reduce the therapeutic burden so more patients can stay on treatment...

...

in the hope of​ preserving vision for the long term.

AXPAXLI™ (also known as OTX-TKI), an investigational axitinib hydrogel administered by intravitreal injection, is currently in Phase 3 clinical trials for wet AMD 

...

in the hope of​ preserving vision for the long term.

DISEASE BURDEN

Retinal disease is one 
of the leading causes 
of blindness

1.8M

Americans9

Wet Age-Related Macular Degeneration (AMD)

6.4M

Americans9

Non-Proliferative Diabetic Retinopathy (NPDR) 

1.7M

Americans9

Diabetic Macular
Edema (DME) 

WET AMD TREATMENT BURDEN

Current treatment imposes a significant burden on patients and care partners15

Patient Burden

90% of patients currently require injections every 1-3 months, impacting and disrupting lives14,19

Care Partner Burden 

Up to 12 days off from work per year may be needed from care partners for treatment visits19

Poor Long-Term Outcomes 

Frequent injections may result in decreased adherence and retinal fluid fluctuations, which are associated with poor long-term outcomes21

REDEFINING TREATMENT

Ocular aims to transform the treatment of retinal disease

We aim to reduce the therapeutic burden so more patients can stay on treatment…in the hope of preserving vision for the long term. 

Ocular’s investigational therapy, AXPAXLITM (axitinib intravitreal hydrogel), also known as OTX-TKI, is currently in Phase 3 clinical trials for wet AMD   

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latest news

Explore our
pipeline​

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upcoming events

References

1. Wang W, et al. Int J Mol Sci. 2018;19(6):1816.2. Di Carlo E, et al. J Clin Med. 2021;10(15):3297. 3. Market Scope. 2024 Retinal Pharmaceuticals Market Report: Wet AMD and Other Exudative Diseases. St. Louis, MO: Market Scope, LLC. 2024. 4. Gualino V, et al. J Fr Ophtalmol. 2020;43:1047-1053. 5. Market Scope. Ophthalmic Market Trends: Quarterly US Retina Edition. St. Louis, MO: Market Scope, LLC. 2025. 6. Evans RN, et al. JAMA Ophthalmol. 2020;138(10):1109.